除了小分子抑制剂,核酸技术也开始在ACH治疗中得到应用。Ribomic开发的RBM-007,通过限制FGF2和FGFR3激活变体之间的过度相互作用发挥功能。2期临床结果显示,RBM-007的疗效与Vosoritide相近(1.5厘米/年),甚至有一名受试者年增长5厘米,且该试验中包括2周一次的注射频率,是当前在研药物中最长的给药间隔。
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What about other solutions? In the era of Docker we are primed to think about portability. Surely we could find a solution to directly leverage our existing C# codebase. What about running the services locally on specific ports? That won’t work on consoles. What about C# to C++ solutions like Unity’s IL2CPP? Proprietary and closed source. None of the immediately obvious solutions were viable here.,推荐阅读51吃瓜获取更多信息
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